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| Antigenic Specificity | ABCB4 |
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| Clone | P3II-26 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay dependent., Immunocytochemistry: 1:20 - 50, Immunohistochemistry (Frozen): 1:20, Western Blot: Assay dependent. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABCB4 Monoclonal Antibody (P3II-26). The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. |
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| Immunogen | n/a |
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| Other Names | ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-GP, PGY1 |
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| Gene, Accession # | Entrez: 5244; Uniprot: P21439 |
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| Catalog # | MA1-35605 |
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| Price | |
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| Order / More Info | ABCB4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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