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產(chǎn)品名稱

CD16 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.

產(chǎn)品貨號

T-1373.0200

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

200 ug

產(chǎn)品品牌

PENINSULA LABORATORIES INTERNATIONAL, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CD16 (human)
Clone	c127
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	purified
Size	200 ug
Concentration	n/a
Applications	IHC
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Marker for NK cells, monocytes and macrophages, and neutrophils. Monoclonal antibody c127 recognizes CD16, the low affinity receptor for IgG (Fc?RIII). CD16 is expressed on the majority of NK cells, on granulocytes, monocytes and macrophages, and on a subset of T cells. CD16 is involved in antibody-dependent cellular cytotoxicity (ADCC). This molecule is encoded by Fc?RIII-A or Fc?RIII-B genes. The genetic heterogeneity of Fc?RIII generates alternative membrane-anchored proteins with distinct signaling capacities when cross-linked by immune complexes. CD16 exists in two distinct forms, as a a single-pass type I integral membrane protein (CD16a), and as a glycosyl phosphatidyl inositol (GPI) form (CD16b). In humans, the transmembrane form is expressed on NK cells and macrophages while the GPI linked form is expressed on granulocytes. Antibody c127 has been described to detect both forms. However, immunohistochemically it reacts mainly with granulocytes. Application: IHC (f), FACS
Immunogen	n/a
Other Names	n/a
Gene, Accession #	n/a
Catalog #	T-1373.0200
Price
Order / More Info	CD16 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
Product Specific References	n/a
產(chǎn)品資料

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