| 產(chǎn)品詳情 |
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| Product Name | Dimethylenastron |
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| Description | Inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Arrests mitosis, triggers apoptosis and up-regulates Hsp-70 expression in multiple human myeloma cell lines. Also inhibits the growth of several types of cancer cell lines (EC50 values are 330, 603, 743 and 881 nM in HCT116, Htert-HME1, BxPC3, K562 and NCI-H1299 cancer cells, respectively). Suppresses the migration and invasion of PANC1 cells in vitro. Cytoprotective. Purity 99%. MW (observed): 302.39 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone |
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| Gene, Accession, CAS # | CAS: 863774-58-7 |
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| Catalog # | 5261/50 |
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| Price | |
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| Order / More Info | Dimethylenastron from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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