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產(chǎn)品名稱

DMH-1 from TOCRIS BIOSCIENCE

產(chǎn)品貨號(hào)

4126/10

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

10 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	DMH-1
Description	Selective inhibitor of bone morphogenic protein (BMP) type-I receptor activin receptor-like kinase 2 (ALK2) receptor (IC50 = 108 nM [Hao et al., 2010] or 12.6 nM [Mohedas et al., 2013] in in vitro kinase assays). Exhibits 6- and 19-fold selectivity for ALK-2 over ALK-1 and ALK-3, respectively, and no significant inhibition of AMPK, ALK5, KDR (VEGFR-2) or PDGFRβ receptors. Blocks BMP4-induced phosphorylation of Smads 1, 5 and 8 in HEK293 cells. Promotes neurogenesis in human induced pluripotent stem cells (iPSCs) when used in combination with SB 431542 (Cat. No. 1614). Purity 98%. MW (observed): 380.44
Size	10 mg
Concentration	n/a
Applications	n/a
Other Names	4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Gene, Accession, CAS #	CAS: 1206711-16-1
Catalog #	4126/10
Price
Order / More Info	DMH-1 from TOCRIS BIOSCIENCE
Product Specific References	PubMed: 23563587, 23928500, 25579684, 25806427, 26110906, 26215036, 26655496, 27320041
產(chǎn)品資料

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