| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | ORAI1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 100 μg |
| Concentration | n/a |
| Applications | Immunocytochemistry: 20 μg/mL, Immunofluorescence: 20 μg/mL, Immunohistochemistry: 10 μg/mL, Western Blot: 1 μg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ORAI1 Polyclonal Antibody. Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one form of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | Entrez: 109305, 84876; Uniprot: Q8BWG9, Q96D31 |
| Catalog # | PA5-20322 |
| Price | |
| Order / More Info | ORAI1 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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