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產品名稱

Autophagy Assay Kit (blue fluorescence) from AAT BIOQUEST, INC.

產品貨號

23000

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

200 tests

產品品牌

AAT BIOQUEST, INC.

產品概述

產品詳情

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Product Name	Autophagy Assay Kit (blue fluorescence)
Description	Cell Meter? Autophagy Assay Kit Blue Fluorescence. Autophagy is an evolutionarily conserved degradation process that targets long-lived proteins, organelles, and other cytoplasmic components for degradation via the lysosomal pathway. The autophagy pathway is complementary to the action of the ubiquitin-proteasome pathway which typically degrades short-lived proteins. Activation of the autophagy pathway is required for multiple cellular roles, including survival during starvation, the clearance of intracellular components, development, and immunity. In the absence of stress, autophagy serves a house-keeping function, removing damaged organelles and cellular components preventing cytotoxic effects. Decreases and defects in autophagy have been implicated in multiple diseases, for example Huntingtons, Alzheimers, and Parkinsons. In terms of cancer development, autophagy seems to play multiple roles. Decreased or absent expression of certain autophagy proteins, such as Beclin-1 and Bif-1, increases tumor susceptibility in mice while the overexpression of these proteins can repress cancer cell growth. However, autophagy is critical for the survival of cancer cells within the nutrient poor and hypoxic core of solid tumors. Cell Meter? Autophagy Kit employs Autophagy Blue? as a specific autophagosome marker to analyze the activity of autophagy. The assay is optimized for direct detection of autophagy in both detached and attached cells. The kit provides all the essential components for the assay protocol. Cell Meter? Autophagy Kit is suitable for fluorescence microscope, fluorescence microplate reader and flow cytometer. Autophagy Blue? has fluorescence excitation and emission at Ex/Em = 333/518 nm.
Size	200 tests
Concentration	n/a
Applications	Biossay, Fluorometric
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	23000
Price
Order / More Info	Autophagy Assay Kit (blue fluorescence) from AAT BIOQUEST, INC.
Product Specific References	n/a
產品資料

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