| 產(chǎn)品詳情 |
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| Antigenic Specificity | CHN2 |
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| Clone | E.584.10 |
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| Host Species | Rat |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CHN2 Monoclonal Antibody (E.584.10). This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice var |
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| Immunogen | n/a |
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| Other Names | OTTHUMP00000202260; beta chimerin; beta-chimaerin; beta-chimerin; rho GTPase-activating protein 3; rho-GTPase-activating protein 3 |
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| Gene, Accession # | Entrez: 1124, 69993, 84031; Uniprot: P52757, Q03070, Q80XD1 |
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| Catalog # | MA5-14967 |
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| Price | |
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| Order / More Info | CHN2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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