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產(chǎn)品名稱

IRS1 Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

AHO1322

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	IRS1
Clone	529Q21
Host Species	Mouse
Reactive Species	human, mouse, rat
Isotype	IgG1, kappa
Format	purified
Size	100 μg
Concentration	n/a
Applications	Western Blot: Assay Dependent
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	IRS1 Monoclonal Antibody (529Q21). Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS-1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS-1 degradation pathways are not well understood. IRS-1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS-1 phosphorylation and subsequent degradation an attractive therapeutic option. To date there have been four subtypes identified: IRS-1,2,3, and 4, with
Immunogen	n/a
Other Names	IRS-1, IRS1, Insulin receptor substrate-1
Gene, Accession #	Entrez: 16367, 25467, 3667; Uniprot: P35568, P35569, P35570
Catalog #	AHO1322
Price
Order / More Info	IRS1 Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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