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| Antigenic Specificity | PCID2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Western Blot: 1.0 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PCID2 Polyclonal Antibody. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associa |
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| Immunogen | n/a |
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| Other Names | F10, PCI domain containing 2, RP11-98F14.6 |
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| Gene, Accession # | Entrez: 100067141, 100355258, 100713598, 234069, 361182, 476994, 492509, 55795, 617943; Uniprot: Q2TBN6, Q5JVF3, Q5U3P0, Q8BFV2 |
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| Catalog # | PA5-70296 |
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| Price | |
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| Order / More Info | PCID2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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