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產(chǎn)品名稱

Decitabine from ARBOR ASSAYS, INC.

產(chǎn)品貨號

P015-10MG

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

10 mg

產(chǎn)品品牌

ARBOR ASSAYS, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Decitabine
Description	Cytosine analog, that when incorporated into DNA, acts as a suicide substrate for DNA methyltransferase. Inhibits DNA methyltransferase and results in DNA hypomethylation and activation of silent genes. Chemotherapeutic agent; suppresses growth of human tumor cell lines. Demethylates differentiation-related genes; reverses embryonic stem cell differentiation. Decitabine is an epigenetic modifier that gives rise to DNA demethylation (hypomethylation) and gene activation by remodeling ``opening'' chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation. This remodeling of chromatin structure allows transcription factors to bind to the promoter regions, assembly of the transcription complex, and gene expression.
Size	10 mg
Concentration	n/a
Applications	Activator or Inhibitor
Other Names	DNA Methyltransferase inhibitor, Dacogen, 5-aza-2'-deoxycytidine,
Gene, Accession, CAS #	n/a
Catalog #	P015-10MG
Price
Order / More Info	Decitabine from ARBOR ASSAYS, INC.
Product Specific References	n/a
產(chǎn)品資料

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