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產(chǎn)品名稱

CD279 Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

367408

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 tests

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	CD279
Clone	NAT105
Host Species	Mouse
Reactive Species	human
Isotype	IgG1, κ
Format	Alexa Fluor? 488 conjugate
Size	100 tests
Concentration	n/a
Applications	Flow Cytometry (FC)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Alexa Fluor? 488 anti-human CD279 (PD-1). Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune diseases. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1, CD274) and PD-L2 (B7-DC, CD273) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The interaction with CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Immunogen	YT cell line.
Other Names	PD1
Gene, Accession #	Gene ID: 5133
Catalog #	367408
Price
Order / More Info	CD279 Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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