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        產(chǎn)品名稱 CD279 Antibody from BIOLEGEND
        產(chǎn)品貨號 367423
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 25 tests
        產(chǎn)品品牌 BIOLEGEND
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityCD279
        CloneNAT105
        Host SpeciesMouse
        Reactive Specieshuman
        IsotypeIgG1, κ
        FormatBrilliant Violet 510? conjugate
        Size25 tests
        Concentrationn/a
        ApplicationsFlow Cytometry (FC)
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionBrilliant Violet 510? anti-human CD279 (PD-1). Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune diseases. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1, CD274) and PD-L2 (B7-DC, CD273) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The interaction with CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
        ImmunogenYT cell line.
        Other NamesPD1
        Gene, Accession #Gene ID: 5133
        Catalog #367423
        Price
        Order / More InfoCD279 Antibody from BIOLEGEND
        Product Specific Referencesn/a
        產(chǎn)品資料
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