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產(chǎn)品名稱

Interleukin 17A (IL17A) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號

ABIN1683689

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Interleukin 17A (IL17A)
Clone	polyclonal
Host Species	Rabbit
Reactive Species	mouse, rat, human
Isotype	n/a
Format	affinity purified
Size	50 μg
Concentration	n/a
Applications	Western Blotting (WB),Immunohistochemistry (IHC),Immunofluorescence (IF)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	IL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by Th17 cells, a distinct CD4+ T cell lineage . IL-17A stimulates the production of the pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity . IL-17A is intimately involved in mucosal immunity against bacterial infections and has a putative role in some autoimmune disorders . IL-17A effects appear to be exerted primarily through binding to the IL-17RA . IL-17A binding induces production of cytokines, chemokines and other proteins through activation of the Erk1/2 MAP kinase, PI3K/Akt, p38, and NF-kappaB pathways (3,4, 6). Phosphorylation of some Jaks and Stats has been observed. Synonyms: IL17A,CTLA8,IL-17,IL-17A,IL17 ,
Immunogen	Recombinant protein of human IL17A
Other Names	Il17\|IL17A\|CTLA8\|IL-17\|IL-17A\|IL17\|Ctla-8\|Ctla8\|CTLA-8\|ChIL-17\|IL-17F
Gene, Accession #	Gene ID: 3605,16171,301289
Catalog #	ABIN1683689
Price
Order / More Info	Interleukin 17A (IL17A) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

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