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| Antigenic Specificity | CD152 |
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| Clone | UC10-4B9 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | Brilliant Violet 421? conjugate |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 421? anti-mouse CD152. CD152, also known as?CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation. |
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| Immunogen | Mouse CTLA-4-mouse IgG2a fusion protein |
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| Other Names | Cytotoxic T Lymphocyte-Associated Antigen-4, CTLA-4, Ly-56 |
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| Gene, Accession # | Gene ID: 12477 |
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| Catalog # | 106312 |
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| Price | |
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| Order / More Info | CD152 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20538992 |
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