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產(chǎn)品名稱

CD152 Antibody from BIOLEGEND

產(chǎn)品貨號

106204

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	CD152
Clone	9H10
Host Species	Syrian Hamster
Reactive Species	mouse
Isotype	IgG
Format	purified, azide-free
Size	500 μg
Concentration	n/a
Applications	ELISA, Flow Cytometry (FC), Block, Costim
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	LEAF? Purified anti-mouse CD152. CD152 is a 33 kD member of the immunoglobulin superfamily also known as CTLA-4 or Ly-56. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance, as well as the development of protective immunity and thymocyte regulation. The 9H10 antibody can enhance T cell co-stimulation by blocking CTLA-4 interactions with the B7 co-receptors, favoring CD28 interactions.
Immunogen	Mouse CTLA-4-human IgG1 fusion protein
Other Names	Cytotoxic T Lymphocyte-Associated Antigen-4, CTLA-4, Ly-56
Gene, Accession #	Gene ID: 12477
Catalog #	106204
Price
Order / More Info	CD152 Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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