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| Antigenic Specificity | CD80 |
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| Clone | 16-10A1 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse, cross-reactivity: dog |
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| Isotype | IgG |
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| Format | Alexa Fluor? 647 conjugate |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC-F |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor? 647 anti-mouse CD80. CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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| Immunogen | CHO cell line transfected with mouse B7 (CD80) |
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| Other Names | B7-1, B7, Ly-53 |
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| Gene, Accession # | Gene ID: 12519 |
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| Catalog # | 104717 |
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| Price | |
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| Order / More Info | CD80 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20624888,21276089,23754785 |
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