| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | CD366 (Tim-3) |
| Clone | B8.2C12 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1, κ |
| Format | purified |
| Size | 500 μg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-mouse CD366 (Tim-3). CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
| Immunogen | mTim-3 protein/Freund adjuvant |
| Other Names | T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366 |
| Gene, Accession # | Gene ID: 171285 |
| Catalog # | 134002 |
| Price | |
| Order / More Info | CD366 (Tim-3) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 21276089 |
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