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        產(chǎn)品名稱 Neurofilament Medium Protein (non-phosphorylated), (phosphorylated) Antibody from ANTIBODIES-ONLINE GmbH
        產(chǎn)品貨號 ABIN94435
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 0.1 mg
        產(chǎn)品品牌 ANTIBODIES-ONLINE GmbH
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityNeurofilament Medium Protein (non-phosphorylated), (phosphorylated)
        CloneNF-09
        Host SpeciesMouse
        Reactive Speciesmammalian
        IsotypeIgG2a
        FormatProtein A purified
        Size0.1 mg
        Concentrationn/a
        ApplicationsImmunocytochemistry (ICC),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionNeurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons. NFs in most vertebrates are composed of three different polypeptide chains with different molecular weights -, neurofilament medium protein (NF-M), high (NF-H) and light protein (NF-L), which share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm. NF-M protein tail-mediated interactions of neurofilaments are critical for size and cytoskeletal architecture of axons, and are mediated, in part, by the highly phosphorylated tail domain of this protein. NF-M phosphorylation and O-GlcNAcylation are regulated reciprocally and affect its translocation and filament formation and function. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.
        ImmunogenPellet of porcine brain cold stable proteins after depolymerization of microtubules.
        Other Namesn/a
        Gene, Accession #n/a
        Catalog #ABIN94435
        Price
        Order / More InfoNeurofilament Medium Protein (non-phosphorylated), (phosphorylated) Antibody from ANTIBODIES-ONLINE GmbH
        Product Specific ReferencesPubMed: 10732731, 8468353, 14662746, 17687114
        產(chǎn)品資料
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