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| Antigenic Specificity | NEFM |
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| Clone | 3H11 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 3-5 μg/mL, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): 1:50-1:500, Immunohistochemistry (PFA fixed): Assay Dependent, Immunoprecipitation: Assay dependent, Western Blot: 1:100-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NEFM Monoclonal Antibody (3H11). Neurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons. NFs, in most vertebrates, are composed of three different polypeptide chains with different molecular weights - neurofilament medium protein (NF-M), high (NF-H) and light protein (NF-L), which share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm. NF-M protein tail-mediated interactions of neurofilaments are |
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| Immunogen | n/a |
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| Other Names | NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3 |
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| Gene, Accession # | Entrez: 24588, 4741; Uniprot: P07197, P12839 |
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| Catalog # | MA1-2011 |
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| Price | |
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| Order / More Info | NEFM Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11967234 |
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