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| Antigenic Specificity | TAB2 |
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| Clone | G.188.0 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TAB2 Monoclonal Antibody (G.188.0). The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
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| Immunogen | n/a |
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| Other Names | OTTHUMP00000017388; TAB-2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2 |
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| Gene, Accession # | Entrez: 23118, 308267, 68652; Uniprot: Q5U303, Q99K90, Q9NYJ8 |
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| Catalog # | MA5-14818 |
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| Price | |
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| Order / More Info | TAB2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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