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產(chǎn)品名稱

IRAK4 Antibody from BOSTER BIO

產(chǎn)品貨號

PA1942

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	IRAK4
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat (predicted: hamster)
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 4(IRAK4) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. IRAK-4(interleukin-1 receptor-associated kinase 4), also called REN64, in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. Scott(2002) mapped the REN64/IRAK4 gene to chromosome 12 based on similarity between the REN64 sequence(GenBank AF155118) and a chromosome 12 clone(GenBank AC093012). Functional analysis by Li et al.(2002) determined that IRAK4, like IRAK1 and Pelle, has auto- and cross-phosphorylation kinase activity. Precipitation and binding analyses showed weak interaction between IRAK4 and IRAK1, but IRAK4 did not interact with other IRAK family members. Overexpressed IRAK4 interacted with MYD88 and TRAF6 and activated mitogen-activated protein kinase(MAPK) and nuclear factor kappa-B(NFKB) pathways.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK4(45-59aa DDRYNQFHIRRFEAL), identical to the related rat and mouse sequences.
Other Names	Interleukin-1 receptor-associated kinase 4;IRAK-4;2.7.11.1;Renal carcinoma antigen NY-REN-64;IRAK4;
Gene, Accession #	IRAK4, UniProt: Q9NWZ3
Catalog #	PA1942
Price
Order / More Info	IRAK4 Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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