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產(chǎn)品名稱

XIAP Antibody from BOSTER BIO

產(chǎn)品貨號(hào)

PA1512

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100ug (sample available)

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	XIAP
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat (predicted: rabbit)
Isotype	n/a
Format	immunogen affinity purified
Size	100ug (sample available)
Concentration	500ug/ml.
Applications	IHC, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB, IHC-P in Human;Mouse;Rat. No cross reactivity with other proteins. BIRC4, baculoviral IAP repeat-containing protein 4 is also known as XIAP(X-linked inhibitor of apoptosis protein). The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human XIAP(14-34aa ADINKEEEFVEEFNRLKTFAN), different from the related mouse sequence by two amino acids.
Other Names	E3 ubiquitin-protein ligase XIAP;6.3.2.-;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked IAP;XIAP;API3, BIRC4, IAP3;
Gene, Accession #	XIAP, UniProt: P98170
Catalog #	PA1512
Price
Order / More Info	XIAP Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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