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產(chǎn)品名稱

Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (N-Term), (aa 4-31) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN1169062

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (N-Term), (aa 4-31)
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	unconjugated
Size	50 μg
Concentration	n/a
Applications	Immunoprecipitation (IP),Western Blotting (WB)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	TRIF is involved in innate immunity against invading pathogens. It is an adaptor used by TLR3 and TLR4 (through TICAM-2) to mediate NF-kappaB and interferon-regulatory factor (IRF) activation and to induce apoptosis. Ligand binding to TLR3 and TLR4 results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappaB and FADD respectively. TRIF is ubiquitously expressed with higher levels in liver.
Immunogen	Synthetic peptide corresponding to aa 4-31 (T4GPSLPSAFDILGAAGQDKLLYLKHKLK31) of N-terminal human TRIF.
Other Names	IIAE6\|MyD88-3\|PRVTIRB\|TICAM-1\|TRIF\|AW046014\|AW547018\|trif
Gene, Accession #	Gene ID: 148022
Catalog #	ABIN1169062
Price
Order / More Info	Toll-Like Receptor Adaptor Molecule 1 (TICAM1) (N-Term), (aa 4-31) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	PubMed: 16964262, 17138826, 18756281
產(chǎn)品資料

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