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| Antigenic Specificity | LIMD1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 500 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LIMD1 Polyclonal Antibody. The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing three LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is downregulated in lung cancer. |
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| Immunogen | n/a |
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| Other Names | LIM domain-containing protein 1 |
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| Gene, Accession # | Entrez: 8994; Uniprot: Q9UGP4 |
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| Catalog # | PA5-32475 |
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| Price | |
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| Order / More Info | LIMD1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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