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        產(chǎn)品名稱 Human TNFAIP3 Antibody from CREATIVE DIAGNOSTICS
        產(chǎn)品貨號 CABT-L744
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 n/a
        產(chǎn)品品牌 CREATIVE DIAGNOSTICS
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityHuman TNFAIP3
        CloneTO18-42
        Host SpeciesRabbit
        Reactive Specieshuman
        IsotypeIgG
        Formatunconjugated
        Sizen/a
        Concentrationn/a
        ApplicationsWB, ICC/IF, IHC, FC
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionRabbit Anti-Human TNFAIP3 monoclonal antibody for WB, ICC/IF, IHC, FC. A20 is a Cys2/Cys2 zinc finger protein that is induced by a variety of inflammatory stimuli and regulates gene expression. Specifically, A20 is induced by tumor necrosis factor (TNF) and interleukin 1 (IL-1), and acts as a negative regulator of nuclear factor κ B (NFκB) gene expression. By inhibiting NFκB activation, A20 plays a critical role in terminating NFκB responses to various stimuli. Although the C-terminal region of A20 contains seven zinc finger domains, only four of these domains are required for in vitro inhibition of TNF-induced NFκB activation. A20 also interacts with several other proteins, such as TRAF2, TRAF6 and IκB kinase (IKK) β protein, and can thereby inhibit cell death. TXBP151, a novel A20-binding protein, may mediate the anti-apoptotic activity of A20. Involved in the negative feedback regulation of signal transduction, A20 and A20-binding proteins may be useful as novel therapeutic tools in the treatment of a variety of diseases.
        ImmunogenRecombinant Protein
        Other Namesn/a
        Gene, Accession #Gene ID: 7128, UniProt: P21580
        Catalog #CABT-L744
        Price
        Order / More InfoHuman TNFAIP3 Antibody from CREATIVE DIAGNOSTICS
        Product Specific Referencesn/a
        產(chǎn)品資料
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