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| Antigenic Specificity | ACT1 |
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| Clone | 9ACT12 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-5 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ACT1 Monoclonal Antibody (9ACT12), eBioscience?. This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expres |
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| Immunogen | n/a |
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| Other Names | RP3-487J7.3, ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, PSORS13; NFkB-activating protein ACT1; TRAF3-interacting protein 2; adapter protein CIKS; connection to IKK and SAPK/JNK; nuclear factor NF-kappa-B activator 1 |
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| Gene, Accession # | Entrez: 10758; Uniprot: O43734 |
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| Catalog # | 14-4040-82 |
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| Price | |
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| Order / More Info | ACT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23066157, 23175766 |
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