| 產(chǎn)品詳情 |
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| Antigenic Specificity | Ticam2 |
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| Clone | CBYJT-3128 |
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| Host Species | Recombinant Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rat Anti-Ticam2 Recombinant Antibody (CBYJT-3128). Provided herein is a Rat monoclonal antibody, which binds to Ticam2 (Toll-Like Receptor Adaptor Molecule 2). The antibody can be used for immunoassay techniques, such as ICC. Ticam2 plays a role as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Ticam2 physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. Ticam2 may also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. It is involved in IL-18 signaling and is propo |
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| Immunogen | E. coli-derived recombinant mouse TRAM/TICAM2, Met1-Ala232, Accession # Q8BJQ4 |
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| Other Names | TRAM; Tirp; Trif; TICAM-2; B430113A10 |
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| Gene, Accession # | Gene ID: 225471, UniProt: Q8BJQ4 |
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| Catalog # | CBMAB-T2396-YJ |
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| Price | |
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| Order / More Info | Ticam2 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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