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產(chǎn)品名稱(chēng)

VEGF-R2/KDR ELISA from ALPCO

產(chǎn)品貨號(hào)

61-KDRHU-E01

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

96 wells

產(chǎn)品品牌

ALPCO

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	VEGF-R2/KDR ELISA
Description	VEGF-A (also called VEGF) and its receptors represent the best characterized signalling pathway in developmental and tumour angiogenesis. VEGF-A binds to two receptor-tyrosine kinases: VEGFR-1/Flt-1 and VEGFR-2/KDR. VEGFR-2 is the major mediator of the mitogenic, angiogenic and permeability-enhancing effects of VEGF-A. The VEGFR's possess an approximately 750 amino acid residue extracellular domain, which is organized into seven immunoglobulin (Ig)- like folds. This extracellular domain is followed by a single transmembrane region, a juxtamembrane domain, a split tyrosine-kinase domain interrupted by a 70-amino acid kinase insert and a C-terminal tail. Alternative splicing or proteolytic processing of VEGFR's give rise to secreted variants of VEGFR-2, also called soluble VEGFR-2. Although the VEGFR's are primarily expressed in the vascular system, sensitive methods like sandwich ELISA's have allowed the detection of VEGFR expression in non-endothelial cells like hematopoietic stem cells. Besides its putative role as a surrogate marker for tumour angiogenesis, naturally occurring sVEGFR-2 is a molecular regulator for VEGF and VEGFR signalling. Sample Types: Human cell culture, citrate plasma, EDTA plasma, heparin plasma, serum. Sample Size: 50 μL. Range: 78 - 5,000 pg/mL. Sensitivity: 7.0 pg/mL. Time: 3hr 30min
Size	96 wells
Concentration	n/a
Applications	Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures.
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	61-KDRHU-E01
Price
Order / More Info	VEGF-R2/KDR ELISA from ALPCO
Product Specific References	n/a
產(chǎn)品資料

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