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產(chǎn)品名稱

KMT5A, 195-352aa, Human, His-tag, Baculovirus from ATGen

產(chǎn)品貨號(hào)

ATGP3812

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

250ug, 50ug, 10ug

產(chǎn)品品牌

ATGen

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	KMT5A, 195-352aa, Human, His-tag, Baculovirus
Description	Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 5mM DTT, 0.2M NaCl, 1mM EDTA, 50% glycerol.. KMT5A, also known as N-lysine methyltransferase KMT5A isoform 1, is an enzyme which catalyzes mono-methylation of histone H4 at lysine 20 (H4K20me1). It is implicated in cell-cycle-dependent transcriptional silencing and mitotic regulation in metazoans. It acts as a barrier to prevent cellular senescence through chromatin-mediated regulation of senescence-associated metabolic remodeling. It mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. The loss of KMT5A concurrently stimulate nucleolar function and retinoblastoma protein-mediated mitochondrial metabolism. Recombinant human KMT5A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size	250ug, 50ug, 10ug
Concentration	n/a
Applications	SDS-PAGE
Other Names	N-lysine methyltransferase KMT5A isoform 1, KMT5A, PR-Set7, SET07, SET8, SETD8
Gene, Accession, CAS #	NP 065115
Catalog #	ATGP3812
Price
Order / More Info	KMT5A, 195-352aa, Human, His-tag, Baculovirus from ATGen
Product Specific References	n/a
產(chǎn)品資料

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