| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD122 |
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| Clone | 5H4 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD122 (IL-2Rβ). CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
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| Immunogen | Rat myeloma YB2/0 transfected with truncated mouse Il-2Rβ cDNA |
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| Other Names | IL-2 Receptor β chain, IL-2Rβ |
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| Gene, Accession # | Gene ID: 16185 |
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| Catalog # | 105902 |
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| Price | |
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| Order / More Info | CD122 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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