| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | CD279 (PD-1) |
| Clone | RMP1-14 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC), IHC, Western Blot (WB), FA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GoInVivo? Purified anti-mouse CD279 (PD-1). CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells). |
| Immunogen | Mouse PD-1 transfected BHK cells |
| Other Names | Programmed Death-1, PD1 |
| Gene, Accession # | Gene ID: 18566 |
| Catalog # | 114114 |
| Price | |
| Order / More Info | CD279 (PD-1) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 17003438,20351188,21094289 |
| 產(chǎn)品資料 |
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