| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD279 (PD-1) |
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| Clone | RMP1-14 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified, azide-free |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, Western Blot (WB), FA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF? Purified anti-mouse CD279 (PD-1). CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells). |
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| Immunogen | Mouse PD-1 transfected BHK cells |
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| Other Names | Programmed Death-1, PD1 |
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| Gene, Accession # | Gene ID: 18566 |
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| Catalog # | 114108 |
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| Price | |
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| Order / More Info | CD279 (PD-1) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17003438,20351188,21094289 |
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