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產(chǎn)品名稱(chēng)

CD279 (PD-1) Antibody from BIOLEGEND

產(chǎn)品貨號(hào)

329902

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	CD279 (PD-1)
Clone	EH12.2H7
Host Species	Mouse
Reactive Species	human, African green, baboon, chimpanzee, common marmoset, cynomolgus, rhesus, squirrel monkey
Isotype	IgG1, κ
Format	purified
Size	100 μg
Concentration	n/a
Applications	Flow Cytometry (FC), IHC
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Purified anti-human CD279 (PD-1). Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Immunogen	n/a
Other Names	PD-1
Gene, Accession #	Gene ID: 5133
Catalog #	329902
Price
Order / More Info	CD279 (PD-1) Antibody from BIOLEGEND
Product Specific References	PubMed: 18829748,18981087,19553327,19889785,20100932,21398606,21562156
產(chǎn)品資料

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