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產(chǎn)品名稱

IL4 Antibody from DENDRITICS SAS

產(chǎn)品貨號

DDX0311

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100μg/50μg

產(chǎn)品品牌

DENDRITICS SAS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	IL4
Clone	11B4
Host Species	Mouse
Reactive Species	human
Isotype	IgM
Format	purified
Size	100μg/50μg
Concentration	n/a
Applications	ELISA, IP, Neutralization of IL4 bioactivity
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. 11B4, was produced from a rat immunized with purified human IL4-transfected-COS7 cells. It recognized both E. coli-expressed and mammalian cell-expressed (COS7 and L cell), rhuIL-4 in solution (immunoprecipitation), as well as on solid phase (indirect ELISA and dot-blotting). The 11B4 antibody inhibited IL-4 bioactivity at an IC50 which was 25-50-fold in molar excess of factor. The 11B4 antibody was used to develop an immunoenzymatic assay capable of detecting concentrations less than 100 pg/ml. (Chretien I et al, 1989, J. Immunol. Methods, 1178 (1) : 67-81; Ramanathan L.et al, 1993, Biochemistry, 32 (14) :3549-56).
Immunogen	n/a
Other Names	interleukin
Gene, Accession #	n/a
Catalog #	DDX0311
Price
Order / More Info	IL4 Antibody from DENDRITICS SAS
Product Specific References	n/a
產(chǎn)品資料

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