| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | MMP-12/HME |
|---|
| Clone | 706F9.01 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100μg/50μg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA capture, IP, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes. HME/MMP-12, also called metalloelastase, is reported only in a few cells, including tissue macrophages and hypertrophic chondrocytes. MMP-12 is critical for invasion and destruction in pathologies such as aneurysm and emphysema.The predicted molecular mass of the HME proenzyme is 54 kDa. HME mRNA and protein were detected in human alveolar macrophages. Similar to murine macrophage metalloelastase, HME readily undergoes NH2- and COOH-terminal processing to a mature 22-kDa form. Both recombinant HME expressed in Escherichia coli and native HME derived from human alveolar macrophage-conditioned media degraded insoluble elastin. HME is a unique human metalloproteinase that possesses elastolytic activity and is expressed in alveolar macrophages; MMP-12 mediates smoke-induced inflammation by releasing TNF-alpha from macrophages, with subsequent endothelial activation, neutrophil influx, and proteolytic matrix breakdown caused by neutrophil-derived proteases (Demedts IK et al, Thorax, 61:196-201) |
|---|
| Immunogen | n/a |
|---|
| Other Names | Proteins of the matrix metalloproteinase |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0281 |
|---|
| Price | |
|---|
| Order / More Info | MMP-12/HME Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
日本三级无码,古代继攵女乱h,最新免费一区二区三区
|
骚虎官网,少妇精品高潮7777,麻豆传媒午夜无码精品试看
|
亚洲激情四射,大肚h孕h失禁,成人性大交免费看
|
美女爱操笔网,国产精品久久久久久久免费大片,五月天婷婷丁香综合国产
|
欧美黄色影院,用力边走边做啊h,午夜影院 日韩
|
亚洲成人性爱在线,好黄好紧好爽好湿的免费视频,日韩中文字幕一区二区三区四区
|
成人激情站,激情四射影院,国内自拍第一页
|
人人澡人人爽欧一区,大鸡巴久久久久久,成人无码区免费A片在线软件
久久三级少妇,久久综合国产精品,操逼视频123
|
国产精品久久久久久久毛片,好大好长好紧爽欧美,免费操人网站
|
北条麻妃中文字幕一区,大香蕉天天干,精品传媒一区二区
|
|