| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | TLR3/CD283 |
| Clone | 1210F1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100μg/50μg |
| Concentration | n/a |
| Applications | Flow cytometry, WB, IP, IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The Toll-like receptor (TLR) family has recently emerged as key for sensing microbial infections and triggering inflammatory and innate responses. Ten TLRs have been cloned in humans. They share structural and functional homologies, as they are all able to detect micro-organisms through direct recognition of conserved Pathogen Associated Molecular Patterns (PAMPs) such as bacterial lipopolysaccharide (LPS) or viral double stranded RNA (dsRNA). Ligand recognition is mediated through the C-terminal Leucine Rich Repeat region, while signalling involves the N-terminal Toll/Interleukin-1 Receptor (TIR) domain. TLR3 has been identified as a receptor for dsRNA. Unlike other TLRs, the cytoplasmic tail of TLR3 does not contain a conserved proline residue, whose mutation confers LPS unresponsiveness in C3H/HeJ mice. TLR3 is the only TLR that signals exclusively through the TIR?containing adaptor TRIF (TIR?containing adaptor inducing IFNβ), which activates the transcription factors IRF3 and NFκB, and triggers type I interferon secretion. TLR3 is expressed in various cell types, such as fibroblasts, dendritic cells (DCs), or NK cells. While TLR3 is expressed at the cell surface in fibroblasts, it is mostly found in intracytoplasmic vesicles in DCs. |
| Immunogen | n/a |
| Other Names | Toll-like receptor 3 |
| Gene, Accession # | n/a |
| Catalog # | DDX0477 |
| Price | |
| Order / More Info | TLR3/CD283 Antibody from DENDRITICS SAS |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
|
北条麻妃先锋影音,潘金莲三级野外,91熟女柏欣彤大黑牛自慰
|
亚洲最大黄色网址,国产欧美在线一区,成人夜夜爽
|
国产性爱无码,做暧昧激烈视频全过程,一本色道久久88亚洲精品综合
|
国产精品一线二线,国产又黄又骚,做爱视频软件
|
大鸡巴操逼免费视频,亚洲国产又黄又爽女人高潮的,日日骚影院
|
黄色毛片视频,男人裸体写真集露大乌,成人无码AAAA视频免费看
|
欧美一级特黄AAAAAAA小说,少妇丰满日韩偷拍欧美,大奶一区
|
男人操女人免费视频,亚洲一区二区三区在线,日逼高清无码
|
免费成人黄色,一级黄裸片,91无码人妻精品一区二区三区四
|
小骚逼超碰,欧美三级头,欧美性xxxxx
|
|