| 產品詳情 |
| Edit |   |
| Antigenic Specificity | CD279 |
| Clone | 29F.1A12 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, κ |
| Format | APC-Fire? 750 conjugate |
| Size | 25 μg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | APC/Fire? 750 anti-mouse CD279 (PD-1). CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| Immunogen | PD-1 cDNA followed by PD-1-Ig fusion protein |
| Other Names | Programmed Death-1, PD1 |
| Gene, Accession # | Gene ID: 18566 |
| Catalog # | 135239 |
| Price | |
| Order / More Info | CD279 Antibody from BIOLEGEND |
| Product Specific References | PubMed: 20453843 |
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