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產(chǎn)品名稱

Equine IL10 Antibody from CREATIVE DIAGNOSTICS

產(chǎn)品貨號(hào)

CABT-L138

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

CREATIVE DIAGNOSTICS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Equine IL10
Clone	polyclonal
Host Species	Goat
Reactive Species	equine
Isotype	n/a
Format	biotin conjugate
Size	n/a
Concentration	n/a
Applications	ELISA(Det), WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Goat Anti-Equine IL10 polyclonal antibody for ELISA(Det), WB. Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper 2 (Th2) cells that inhibited the cytokine production by Th1 cells. It is a pleiotropic cytokine that regulates the immune and inflammatory responses of hematopoietic cells. IL-10 has immunosuppressive activities and has been shown to inhibit the effector functions of monocyte/macrophage and CD4+ T cells. Conversely, IL-10 has immunostimulatory activities and can induce the proliferation and cytotoxic activity of CD8+ T cells and NK cells. IL-10 also regulates the growth and differentiation of B cells, mast cells, dendritic cells and neutrophils. The biological activities of IL-10 is mediated by the heteromeric IL-10 receptor complex, which is composed of the ligand-binding IL-10R alpha and the accessory IL-10R beta subunits. Both subunits belong to the class II cytokine receptor family. IL-10R beta bis also utilized as a subunit in the heterodimer receptor complex for IL-22, IL-28 and IL-29. Besides IL-10, five novel cytokines (IL-19,-20,-22,-24, and-26) that share structural and limited sequence homology with IL-10 have been identified. These proteins constitute the IL-10 cytokine family.Equine IL-10 cDNA encodes a 178 amino acid residue (aa) precursor protein with an 18 aa signal peptide and 160 aa mature protein that contains two potential N-linked glycosylation sites. Analogous to human IL-10, equine IL-10 likely exists as nondisulfide-linked homodimers. Equine IL-10 shares 71% and 78% aa sequence homology with mouse and human IL-10, respectively.
Immunogen	Recombinant Protein
Other Names	n/a
Gene, Accession #	UniProt: I1WWX5
Catalog #	CABT-L138
Price
Order / More Info	Equine IL10 Antibody from CREATIVE DIAGNOSTICS
Product Specific References	n/a
產(chǎn)品資料

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