| Edit |   |
|---|
| Antigenic Specificity | CD107a (LAMP-1) |
|---|
| Clone | eBioH4A3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | eFluor 450 conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 μL (0.25 μg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD107a (LAMP-1) Monoclonal Antibody (eBioH4A3), eFluor 450, eBioscience?. CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation. |
|---|
| Immunogen | n/a |
|---|
| Other Names | CD107a, LAMPA, LGP120, CD107 antigen-like family member A, LAMP-1, lysosome-associated membrane glycoprotein 1, lysosome-associated membrane protein 1 |
|---|
| Gene, Accession # | Entrez: 3916; Uniprot: P11279 |
|---|
| Catalog # | 48-1079-42 |
|---|
| Price | |
|---|
| Order / More Info | CD107a (LAMP-1) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 26771955, 26942053, 27560716, 27669461 |
|---|