| 產(chǎn)品詳情 |
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| Antigenic Specificity | Forkhead Box P3 (FOXP3) |
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| Clone | 3G3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | unconjugated |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FoxP3 (Forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. |
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| Immunogen | Full-length His-tagged recombinant murine FoxP3 |
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| Other Names | foxp3|FOXP3|AIID|DIETER|IPEX|PIDX|XPID|JM2|scurfin|sf|RGD1562112 |
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| Gene, Accession # | Gene ID: 50943,20371 |
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| Catalog # | ABIN2749083 |
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| Price | |
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| Order / More Info | Forkhead Box P3 (FOXP3) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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