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| Antigenic Specificity | FOXP3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 μL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Polyclonal Antibody. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as |
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| Immunogen | n/a |
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| Other Names | Scurfin; Forkhead box protein P3; FOXP3; IPEX; |
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| Gene, Accession # | Entrez: 20371, 50943; Uniprot: Q99JB6, Q9BZS1 |
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| Catalog # | PA5-12396 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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