| Edit |   |
|---|
| Antigenic Specificity | FOXP3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Frozen): 1:150, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1:1000-1:5000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | FOXP3 Polyclonal Antibody. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as |
|---|
| Immunogen | n/a |
|---|
| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
|---|
| Gene, Accession # | Entrez: 20371, 50943; Uniprot: Q99JB6, Q9BZS1 |
|---|
| Catalog # | PA1-16877 |
|---|
| Price | |
|---|
| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|