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產(chǎn)品名稱

Neurofilament H (NF-H) Antibody from BIOLEGEND

產(chǎn)品貨號

801705

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

25 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Neurofilament H (NF-H)
Clone	SMI 32
Host Species	Mouse
Reactive Species	human, mouse, rat, other mammalian
Isotype	IgG1, κ
Format	Alexa Fluor? 488 conjugate
Size	25 μg
Concentration	n/a
Applications	IHC-P
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Alexa Fluor? 488 anti-Neurofilament H (NF-H), Nonphosphorylated. Neurofilaments (NF) are approximately 10 nanometer intermediate filaments found in neurons. They are a major component of the neuronal cytoskeleton, and function primarily to provide structural support for the axon and to regulate the axon diameter. There are three major NF subunits, and the names given to these subunits are based upon the apparent molecular mass of the mammalian subunits on SDS-PAGE. The light or lowest NF (NF-L) runs at 68-70 kD. The medium or middle NF (NF-M) runs at about 145-160 kD, and the heavy or highest NF (NF-H) runs at 200-220 kD. However, the actual molecular weight of these proteins is considerably lower due to the highly charged C-terminal regions of the molecules. The level of NF gene expression correlates with the axonal diameter, which controls how fast electrical signals travel down the axon. Mutant mice with NF abnormalities have phenotypes resembling amyotrophic lateral sclerosis. NF immunostaining is common in diagnostic neuropathology. It is useful for differentiating neurons (positive for NF) from the glia (negative for NF).
Immunogen	n/a
Other Names	Neurofilament heavy polypeptide, NF-H, 200 kD neurofilament protein, neurofilament triplet H protein
Gene, Accession #	Gene ID: 4744
Catalog #	801705
Price
Order / More Info	Neurofilament H (NF-H) Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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