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| Antigenic Specificity | RON |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 25 μg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RON Polyclonal Antibody. Macrophage-stimulatin 1 receptor (MST1R/Ron), a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been im |
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| Immunogen | n/a |
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| Other Names | CD136, CDw136, PTK8, RON, MSP receptor, MST1R variant RON30, MST1R variant RON62, PTK8 protein tyrosine kinase 8, RON variant E2E3, c-met-related tyrosine kinase, macrophage-stimulating protein receptor, p185-Ron, soluble RON variant 1, soluble RON variant 2, soluble RON variant 3, soluble R |
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| Gene, Accession # | Entrez: 4486; Uniprot: Q04912 |
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| Catalog # | OPA1-15590 |
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| Price | |
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| Order / More Info | RON Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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