| Edit |   |
|---|
| Antigenic Specificity | WNT5A |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat, dog |
|---|
| Isotype | n/a |
|---|
| Format | biotin conjugate |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | WB, IHC-P |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | WNT5A Polyclonal Antibody, Biotin Conjugated. ? Target Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from human WNT5A. Immunogen Range: 330-380/381 |
|---|
| Other Names | hWNT5A; Protein Wnt-5a; WNT5A |
|---|
| Gene, Accession # | Gene ID: 7474, SwissProt: P41221 |
|---|
| Catalog # | bs-1948R-Biotin |
|---|
| Price | |
|---|
| Order / More Info | WNT5A Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | Saha, Subhrajit, et al.(2016) Nat Commun. PubMed: 27734833 |
|---|