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| Antigenic Specificity | SUMO1 |
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| Clone | T.243.0 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SUMO1 Monoclonal Antibody (T.243.0). SUMO1 is an ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment, via an isopeptide bond, to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved, for instance, in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitinatio |
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| Immunogen | n/a |
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| Other Names | GAP modifying protein 1; OTTHUMP00000202403; OTTHUMP00000202404; OTTHUMP00000202405; OTTHUMP00000202406; OTTHUMP00000202409; OTTHUMP00000202410; SMT3 homolog 3; sentrin; small ubiquitin-related modifier 1; ubiquitin-homology domain protein PIC1; ubiquitin-like protein SMT3C; ubiquitin-like protein UBL1 |
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| Gene, Accession # | Entrez: 22218, 301442, 7341; Uniprot: P63165, P63166, Q5I0H3 |
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| Catalog # | MA5-14877 |
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| Price | |
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| Order / More Info | SUMO1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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