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| Antigenic Specificity | USP33 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 μg/mL, Immunofluorescence: 1-4 μg/mL, Immunohistochemistry: 1:500-1:1000, Western Blot: 0.4 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | USP33 Polyclonal Antibody. Deubiquitinating enzyme involved in various processes such as cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB |
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| Immunogen | n/a |
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| Other Names | VDU1, VHL-interacting deubiquitinating enzyme 1, deubiquitinating enzyme 33, hVDU1, pVHL-interacting deubiquitinating enzyme 1, ubiquitin carboxyl-terminal hydrolase 33, ubiquitin specific protease 33, ubiquitin thioesterase 33, ubiquitin thiolesterase 33, ubiquitin-sp |
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| Gene, Accession # | Entrez: 170822, 23032; Uniprot: Q8R5K2, Q8TEY7 |
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| Catalog # | PA5-52191 |
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| Price | |
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| Order / More Info | USP33 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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