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產(chǎn)品名稱(chēng)

STIMA-1 from BIOVISION, INC.

產(chǎn)品貨號(hào)

9437-50

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

50 mg

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	STIMA-1
Description	STIMA-1 (SH group-targeting compound that induces massive apoptosis) reactivates mutant p53. STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells. STIMA-1 is shown to covalently modify free thiols on mutant p53 in H1299-His175 cells and fully restore its DNA binding activity to the level seen with wild-type p53, resulting in upregulation of p53-dependent gene expression, including p21, PUMA, and Bax. MW: 172.19. Purity ≥97%
Size	50 mg
Concentration	n/a
Applications	n/a
Other Names	2-Vinyl-4H-quinazolinol; SH group-targeting compound that induces massive apoptosis
Gene, Accession, CAS #	CAS: 91634-12-7
Catalog #	9437-50
Price
Order / More Info	STIMA-1 from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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