| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | IL-1RII, Human |
| Clone | 8.5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 100 μg |
| Concentration | 100 μg/ml |
| Applications | FC, immunoassay, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody reacts specificly with Human IL-1RII. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. The IL-1RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signaling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1RI. The decoy IL-1RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | HM2053F |
| Price | |
| Order / More Info | IL-1RII, Human Antibody from HYCULT BIOTECH |
| Product Specific References | n/a |
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