亚洲日韩三级片,视频一区中文字幕,无码不卡永久视频自拍,91人兽,亚洲乱伦网,做爱无码在线,91国内产香蕉,爱爱91视频

<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱(chēng)

Multidrug Efflux Transporter Ligand Screening Kit from CREATIVE BIOMART

產(chǎn)品貨號(hào)

Kit-2094

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

100 assays

產(chǎn)品品牌

CREATIVE BIOMART

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	Multidrug Efflux Transporter Ligand Screening Kit
Description	The MDR1/P-gp Ligand Screening Kit is designed for rapidly screening test compounds for modulation of efflux transporter activity in MDR1-expressing cell lines. The assay uses a lipophilic non-fluorescent P-gp substrate that readily diffuses through the plasma membrane, where it is hydrolyzed to an active fluorophore by cytosolic esterases. The resulting hydrophilic fluorophore is neither membrane permeable nor a substrate for P-gp, hence it remains trapped inside the cell. In MDR1-expressing cell lines, the lipophilic pro-fluorophore is continuously extruded from the cytosol by P-gp, leading to a low intracellular fluorescence. Inhibition of P-gp-mediated efflux by a test compound leads to increased intracellular fluorescence. Specific transporter activity is quantified by comparison with fluorescence accumulated in the presence and absence of a saturating concentration of the included selective P-gp inhibitor. The assay is highly sensitive, has a simple no-wash protocol and is highthroughput adaptable. The kit contains a complete set of reagents sufficient for performing 100 reactions in a 96-well plate format.
Size	100 assays
Concentration	n/a
Applications	Screening and characterization of drugs and new chemical entities for inhibition of native/recombinant MDR1/P-gp efflux transporter.Identification/characterization of cells and cell lines with a high level of MDR1-mediated efflux (i.e. chemotherapy-resistant).
Other Names	n/a
Gene, Accession, CAS #	n/a
Catalog #	Kit-2094
Price
Order / More Info	Multidrug Efflux Transporter Ligand Screening Kit from CREATIVE BIOMART
Product Specific References	n/a
產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>